Preventing Perinatal Depression: Cultural Adaptation of the Mothers and Babies Course in Kenya and Tanzania

Pregnant women and mothers in sub-Saharan Africa are at high risk for perinatal depression, warranting a need to develop culturally tailored interventions prevent depression. This paper documents the process of adapting an evidence-based preventive intervention developed United States, Mothers Babies Course (MBC), fit contexts rural pregnant young children Kenya Tanzania using updated Framework Reporting Adaptations Modifications-Enhanced (FRAME). Data from informant interviews field observations planning implementation phases were used make adaptations modifications MBC through eight aspects FRAME. Follow-up visits reflection meetings with case managers participants indicated that adapted version was well accepted, but fidelity limited due various barriers. The FRAME provided optimal structure outline key intended maximize engagement, delivery, outcomes high-risk settings.